The electrostatic potential and electric field generated by a monofunctional chorismate mutase engineered from the P-protein of E. coli (Structure from A Lee, P. A. Karplus, B. Ganem and J. Clardy, Dept of Chemistry, Cornell Univ.; electrostatic calculations by Daniel Ripoll, CSERG). An imaginary plane intersecting the protein through the two active site regions is colored according to the values of the electrostatic potential (proceeding from low to high in the sequence: dark blue, light blue, green, black, yellow, red). The electric field lines were initiated from a circle contained in the plane, and the direction of the field is indicated by the blue and red lines.