Structural Studies of Endonucleases

A systematic procedure to enumerate secondary structure elements in an unambiguous and reproducible way, and use it to analyze the currently available Xray structures of Type II REases was introduced. Details of this work can be found in:

M.Y. Niv, D.R. Ripoll, J.A. Vila, A. Liwo, E.S. Vanamee, A.K. Aggarwal, H. Weinstein and H.A. Scheraga. (2007). “Topology of type II REases revisited; structural classes and the common conserved core.”  Nucleic Acids Res. 35, 2227-2237. [pdf]